Disease Modelling · AI Bioimaging · Biomimetic Tissue Design

Make the invisible
measurable.

Expert consulting in disease modelling and AI bioimaging — combining 3D biomimetic tissue design with peer-reviewed imaging tools, applied across cancer, fibrosis, and immune research.

0
Years Research
Topology Analyser — Analysis Output
3D Cell–Matrix Structure
3D cell matrix — Topology Analyser output
2.3μm
Avg Pore
87%
Density
3D
Analysis
Discover
Our Vision

Better disease models.
Clearer biological insight.

"Our goal: make the invisible biology of disease measurable, understandable, and actionable."

We believe progress in disease research depends on models that reflect actual biology. By combining biomaterials engineering, mechanobiology, and AI-driven imaging, we develop methods that turn complex biological signals into clear, interpretable data.

Fluorescence microscopy of fibroblast cells in 3D collagen matrix
Fluorescence Microscopy
Fibroblast cells in 3D collagen matrix
Actin (green) · Nucleus (blue) · ECM (white)
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Biomimetic Tissue Design
3D in vitro environments that recapitulate native tissue architecture — enabling precise, physiologically relevant cell–matrix studies.
🤖
AI-Driven Analytics
Intelligent imaging and machine learning to interpret how cells sense and respond to their environment in real time.
🎯
Translational Focus
Accelerating research into clinical impact — across immuno-oncology, regenerative medicine, fibrosis, and drug discovery.
🤝
Research Partnerships
Working with academic groups, clinical teams, and industry partners — across material science, cell biology, and AI-driven imaging.
Research published in
Acta Biomaterialia Elsevier
Scientific Reports Nature Portfolio
Advanced Healthcare Materials Wiley
Biomaterials Science RSC
Biomaterials Elsevier
Capabilities

Tools we built.
Methods we use.

Every tool we use started as a real research problem with no good solution. We wrote the code, validated it in the lab, and published the methods. These tools are what we bring to every engagement — peer-reviewed, lab-validated, and fully documented.

Topology Analyser software UI
Bioimaging 📄 Acta Biomaterialia · 2014
Topology Analyser
Quantify tissue architecture — automatically

Converts raw microscopy images of biological tissue into precise structural measurements — pore sizes, fibre arrangement, density, and spatial patterns — extracted automatically in 2D and 3D. Applied in cancer, fibrosis, and wound healing research.

  • 2D & 3D tissue structure analysis from microscopy images
  • Fully automated — no manual segmentation required
  • Derives physical measurements from optical images
  • Batch processing with structured, exportable outputs
Ask about this in your project →
CellDetection software UI
Bioimaging 📄 Scientific Reports · 2017
CellDetection
AI-powered 3D cell tracking — label-free

Tracks individual cells moving freely through 3D environments — without labels, stains, or manual annotation. Built to follow immune cells through native-like tissue when no tool existed to do it. Used for cell migration, invasion, and behaviour studies.

  • AI cell detection — no labelling or staining needed
  • Tracks hundreds of cells simultaneously across time
  • Speed, direction & displacement — all auto-calculated
  • CSV export & annotated video replay
Ask about this in your project →
What we offer

Better science.
Faster discoveries.

We work with research teams on disease modelling and bioimaging — from experiment design to data analysis. Pick the level of involvement that fits your needs.

🧪
Scientific Consulting
Feasibility assessment and experiment design — science-based input before you commit to a protocol.
Advisory
📊
Data Analysis
Send us your imaging data. Our team analyses it using Topology Analyser and CellDetection, and returns interpreted findings.
Analysis Service
💾
Software Licence
Access our tools directly — run Topology Analyser and CellDetection in your own lab at a basic licence tier.
Self-service
🔧
Retrofit Development
Already have an imaging pipeline or analysis workflow? We adapt and integrate our tools to fit it — no need to rebuild from scratch.
Custom Dev
What consulting includes
🔬
Cell–Matrix Interaction Studies
We design and quantify how cells sense, remodel, and respond to their extracellular matrix — using Topology Analyser for matrix structure and CellDetection for cell behaviour. Both sides of the interaction, in the same experiment.
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3D Disease Model Design
Tissue models that faithfully replicate the architecture and mechanical properties of native tissue — for cancer, fibrosis, inflammation, or immune response. Built for your research question, not a generic protocol.
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Bioimaging Data Analysis
Automated pipelines using our tools to extract structural, spatial, and dynamic measurements from your microscopy data — at scale, with interpreted results.
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Multi-Omics Integration
Connecting genomics, transcriptomics, and proteomics with biomechanical imaging data — linking molecular signals to physical outcomes for a complete picture of disease.
Replace Reduce Refine Our work is grounded in in vitro biomimetic methods — supporting the international 3Rs principle, recognised across 40+ countries.
Work with us

Not sure which option fits?

Tell us what you're working on — we'll suggest the right approach. Engagements range from a single feasibility review to ongoing multi-month collaborations.

  • Academic & industry research teams
  • Pharmaceutical & biotech partners
  • Individual labs & core facilities
  • Custom pipeline & tool integration
Get in touch →
Dr. Jiranuwat Sapudom
🔬 Founder

Research experience
you can work with.

Dr. Jiranuwat Sapudom — biochemist and bioengineer, Research Scientist at NYU Abu Dhabi — brings nearly a decade of hands-on expertise in cell–matrix interactions, mechanobiology, tissue engineering, and multi-omics analysis to every engagement.

The tools we use were built in-house because nothing else was good enough. That same standard applies to every project we take on.

🧬 Mechanobiology 🧫 Tissue Engineering 🔗 Multi-Omics 🚀 Space Biology 💻 AI & Bioimaging
Meet the founder →

Let's talk about your research.

Whether you have a project in mind or just want to explore what's possible — we read every message and reply to every one.

contact@matrixense.com →
🔬 Founder's research profile