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How cells move, and how they pull.

Two short narrated lessons on 3D cell mechanics. Written for university students, useful for anyone starting with migration or traction force analysis. Turn your sound on.

Title slide: How cells move, with coloured cell tracks
Lesson 1 · 13 min

How cells move

Cell migration in 2D and 3D, from a movie to numbers.

  • Why migration matters, and how cells crawl and squeeze
  • Trajectories, speed, directness and the time-step trap
  • Mean squared displacement, the slope α and persistence
  • Migration patterns, and does 2D predict 3D?
Start lesson
Title slide: How cells pull, with a cell among beads
Lesson 2 · 12 min

How cells pull

Traction force in 2D and 3D, and why collagen is hard.

  • Why cells pull: sensing, wound closure, fibrosis, invasion
  • Stress, strain, stiffness and a short history of TFM
  • 2D TFM and the regularised inverse problem
  • 3D collagen: reference, drift, noise, nonlinearity, neighbours
Start lesson

The animations use simulated, illustrative data. Narration voice is synthetic. Questions or corrections: hello@matrixense.com